TC1(C8orf4) Regulates Hematopoietic Stem/Progenitor Cells and Hematopoiesis
نویسندگان
چکیده
منابع مشابه
TC1(C8orf4) Regulates Hematopoietic Stem/Progenitor Cells and Hematopoiesis
Hematopoiesis is a complex process requiring multiple regulators for hematopoietic stem/progenitor cells (HSPC) and differentiation to multi-lineage blood cells. TC1(C8orf4) is implicated in cancers, hematological malignancies and inflammatory activation. Here, we report that Tc1 regulates hematopoiesis in mice. Myeloid and lymphoid cells are increased markedly in peripheral blood of Tc1-delete...
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1Department of Internal Medicine, Division of Cardiology, and 2Departments of Physiology and Developmental Biology, UT Southwestern Medical Center, Dallas, TX; 3Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao-Tong University School of Medicine, Shanghai, China; 4The Methodist Hospital Research Institute, Houston, TX; and 5Departments of Pedia...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0100311